Largo Smiles Dental Center

Your Trusted Dentist in Key Largo, Fl

Upper Keys Main Dental Clinic

Year of Experience
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Your Trusted Dentist in Key Largo, FL

Welcome to Key Largo Smiles Dental Center — a modern dental office located at 103071 Overseas Highway in Key Largo, Florida. Led by Dr. Jenifer Santos, DMD, a board-trained Prosthodontist, our practice provides comprehensive dental care for individuals, families, and visitors throughout the Florida Keys. Whether you need a routine cleaning, a dental emergency, or a complete smile makeover, our team is here to help you feel comfortable, confident, and well cared for.

Since opening our doors in 2021, we have served patients from Key Largo, Tavernier, Islamorada, Marathon, Big Pine Key, and beyond. Our goal is simple: to be the dental home you trust for every stage of life. We offer flexible appointment scheduling, accept most major dental insurance plans, and provide financing options to make high-quality care accessible to every patient we see.

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Patient Satisfaction Rate

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Personalized Treatment Commitment

Modern Dental Care in the Heart of the Florida Keys

Key Largo Smiles Dental Center was built on the belief that every patient deserves personalized, compassionate care in a comfortable environment. Our office combines advanced dental technology with a genuinely warm, patient-first approach — so whether you are coming in for your first visit or your fiftieth, you will always feel welcome.

Our team speaks both English and Spanish, allowing us to effectively serve the diverse community of the Upper Keys. If you prefer to communicate in Spanish during your appointment, simply let us know when you schedule your visit.

We are conveniently located on Overseas Highway — easy to reach whether you live in Key Largo or are traveling through the Keys. Ample parking is available, and our office is designed to make every visit as stress-free as possible.

Tooth Trauma

Complete Dental Services for the Whole Family

From preventive dentistry to advanced restorative and cosmetic treatments, Key Largo Smiles offers a full range of dental services under one roof. You should never have to travel off the island for quality dental care — and with our team, you won’t have to.

Preventive Dentistry

Preventive care is the foundation of long-term oral health. Regular dental exams and professional ….

Restorative Dentistry

When teeth are damaged, decayed, or missing, restorative dentistry brings back both function ….

Restorative Dentistry

Cosmetic Dentistry

A confident smile can change how you feel every day. Our cosmetic services are designed ….

Cosmetic Dentistry
Meet Dr. Jenifer Santos

Meet Dr. Jenifer Santos, DMD — Prosthodontist

Dr. Jenifer Santos is the heart of Key Largo Smiles. A Doctor of Dental Medicine (DMD) and trained Prosthodontist, Dr. Santos earned her degree at the University of Pennsylvania in Philadelphia — one of the top dental schools in the country. She then completed an Advanced Education in General Dentistry (AEGD) residency at the Miami VA Hospital, where she focused on cosmetic dentistry and complex restorative cases. 

Dr. Santos is committed to evidence-based dentistry and stays current with the latest advances in dental technology and technique. Patients consistently describe her as thorough, gentle, and genuinely invested in their long-term oral health. She takes the time to explain every treatment option clearly — so you always feel informed and in control of your care.

Alongside Dr. Santos, our dental team includes experienced hygienists and support staff who share the same commitment to compassionate, patient-centered service. Many patients say they feel treated like family from their very first visit.

What Our Patients Say About Key Largo Dental

Dental Insurance and Financing Options

We believe that cost should never be a barrier to getting the dental care you need. Key Largo Smiles accepts a wide range of dental insurance plans, including:

  • Delta Dental
  • Humana
  • MetLife
  • Blue Cross Blue Shield
  • Most major dental PPO insurance plans

For patients without dental insurance, we offer flexible payment plans and financing options to help spread the cost of treatment. Our front desk team will work with you to find an arrangement that fits your budget. No patient should leave without the care they need because of financial concerns.

Proudly Serving Key Largo and the Upper Florida Keys

Key Largo Smiles Dental Center is located at 103071 Overseas Highway in Key Largo, Florida — right on the main route through the Keys. We are proud to be the dental home for patients throughout the Upper Keys, including:

  • Key Largo
  • Tavernier
  • Islamorada
  • Big Pine Key
  • Marathon
  • Florida City and Homestead

Whether you have lived in the Keys your whole life or just moved to the area, we welcome you to schedule a visit and experience the Key Largo Smiles difference. Our location on Overseas Highway makes us easy to find and easy to reach, no matter where in the Keys you are coming from.

Call us at (305) 451-8005 or stop by our office at 103071 Overseas Highway, Key Largo, FL 33037. We look forward to welcoming you.

Schedule Your Appointment with a Key Largo Dentist Today

Frequently Asked Questions

How much does a dentist visit cost in Key Largo?

The cost of a dental visit depends on the services needed. A routine cleaning and exam typically ranges from $100 to $300 without insurance. With dental insurance such as Delta Dental, Humana, MetLife, or Blue Cross Blue Shield, your out-of-pocket costs for preventive care are often significantly reduced — many plans cover preventive visits at little or no cost. For more complex procedures like dental implants, crowns, or orthodontics, our team will provide a full cost breakdown and discuss financing options before any treatment begins.

How long can a patient go without a dental exam in Florida?

There is no legal requirement in Florida dictating how often patients must visit the dentist, but most dental professionals — including our team — recommend scheduling a checkup and cleaning every six months. Waiting longer than a year between visits significantly increases the risk of undetected tooth decay, gum disease, and other oral health conditions. Some patients with specific risk factors may benefit from more frequent visits, which we will discuss with you during your appointment.

Do you accept dental insurance?

Yes. We accept Delta Dental, Humana, MetLife, Blue Cross Blue Shield, and most major PPO dental insurance plans. When you contact our office to schedule an appointment, our team will verify your dental insurance benefits and explain what your plan covers before your visit. We also offer payment plans for patients without insurance.

What happens if I have a dental emergency?

Call our office immediately at (305) 451-8005. We prioritize emergency patients and do our best to provide same-day appointments during business hours. Common dental emergencies we treat include severe tooth pain, cracked or broken teeth, knocked-out teeth, lost fillings or crowns, swelling or abscess, and dental infections. If your emergency occurs outside of office hours, call our main number for after-hours guidance.

Do you see children?

Yes. We see patients of all ages and provide a welcoming environment for children and families. We recommend that children have their first dental visit by their first birthday or within six months of their first tooth coming in. Our team takes special care to make younger patients feel comfortable and at ease during their appointment.

What happens if I have a dental emergency?

Call our office immediately at (305) 451-8005. We prioritize emergency patients and do our best to provide same-day appointments during business hours. Common dental emergencies we treat include severe tooth pain, cracked or broken teeth, knocked-out teeth, lost fillings or crowns, swelling or abscess, and dental infections. If your emergency occurs outside of office hours, call our main number for after-hours guidance.

Do you see children?

Yes. We see patients of all ages and provide a welcoming environment for children and families. We recommend that children have their first dental visit by their first birthday or within six months of their first tooth coming in. Our team takes special care to make younger patients feel comfortable and at ease during their appointment.

Do you offer services in Spanish?

Yes. Our team is bilingual and provides dental care in both English and Spanish. If you prefer to communicate in Spanish, please let us know when scheduling your appointment and we will make sure a Spanish-speaking team member is available to assist you throughout your visit.

How do I schedule an appointment?

You can schedule an appointment by calling our office at (305) 451-8005, emailing dr.santos@keylargosmiles.com, or using the contact form on our website. New patients are always welcome. Please let us know if it is your first visit, as we will set aside extra time to complete your new patient records and conduct a thorough initial examination.

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